Hydrogels are hydrophilic 3D networks which might be capable of ingest massive quantities of water or organic fluids, and are potential candidates for biosensors, drug supply vectors, vitality harvester gadgets, and carriers or matrices for cells in tissue engineering. Natural polymers, e.g., cellulose, chitosan and starch, have glorious properties that afford fabrication of superior hydrogel supplies for biomedical functions: biodegradability, biocompatibility, non-toxicity, hydrophilicity, thermal and chemical stability, and the excessive capability for swelling induced by facile artificial modification, amongst different physicochemical properties.
Hydrogels require variable time to succeed in an equilibrium swelling as a result of the variable diffusion charges of water sorption, capillary motion, and different modalities. In this examine, the nature, transport kinetics, and the function of water in the formation and structural stability of numerous varieties of hydrogels comprised of pure polymers are reviewed.Since water is an integral half of hydrogels that represent a substantive portion of its composition, there’s a must receive an improved understanding of the function of hydration in the construction, diploma of swelling and the mechanical stability of such biomaterial hydrogels.
The capability of the polymer chains to swell in an aqueous solvent will be expressed by the rubber elasticity concept and different thermodynamic contributions; whereas the charge of water diffusion will be pushed both by focus gradient or chemical potential. An overview of fabrication methods for numerous varieties of hydrogels is offered in addition to their responsiveness to exterior stimuli, together with their potential utility in numerous and novel functions. This overview goals to shed gentle on the function of hydration to the construction and perform of hydrogels. In flip, this overview will additional contribute to the improvement of superior supplies, reminiscent of “injectable hydrogels” and super-adsorbents for functions in the subject of environmental science and biomedicine.
Formation of contractile 3D bovine muscle tissue for development of millimetre-thick cultured steak
Owing to the enhance in the international demand of meat, cultured meat expertise is being developed to bypass a scarcity of meat in the future. However, strategies for development of millimetre-thick bovine muscle tissues with extremely aligned myotubes haven’t but been established. Here, we suggest a tradition technique for establishing 3D-cultured bovine muscle tissue containing myotubes aligned alongside its long-axial course, which contracted in response to electrical stimulation.
First, we optimised the composition of biomaterials utilized in the development and the electrical stimulation utilized to the tissue throughout tradition. Subsequently, we fabricated millimetre-thick bovine muscle tissues containing extremely aligned myotubes by accumulating bovine myoblast-laden hydrogel modules. The microbial content material of the bovine muscle tissue cultured for 14 days was beneath the detection restrict, indicating that the muscle tissues have been sterile, not like business meat. Therefore, the proposed development technique for bovine muscle tissues can be helpful for the manufacturing of clear cultured steak meat simulating actual meat.
The synergistic union of nanomaterials with biomaterials has revolutionized artificial chemistry, enabling the creation of nanomaterial-based biohybrids with distinct properties for biomedical functions. This class of supplies has drawn vital scientific curiosity from the perspective of purposeful extension by way of controllable coupling of artificial and biomaterial parts, leading to enhancement of the chemical, bodily, and organic properties of the obtained biohybrids.
In this overview, we spotlight the forefront supplies for the mixture with biomacromolecules and residing organisms and their advantageous properties in addition to latest advances in the rational design and synthesis of synthetic biohybrids. We additional illustrate the unbelievable variety of biomedical functions stemming from artificially bioaugmented traits of the nanomaterial-based biohybrids. Eventually, we intention to encourage scientists with the software horizons of the thrilling subject of artificial augmented biohybrids.
Current Insights Into 3D Bioprinting: An Advanced Approach for Eye Tissue Regeneration
Three-dimensional (3D) printing is a recreation changer expertise that holds nice promise for all kinds of biomedical functions, together with ophthalmology. Through this rising method, particular eye tissues will be custom-fabricated in a versatile and automated method, incorporating completely different cell varieties and biomaterials in exact anatomical 3D geometries. However, and regardless of the nice progress and prospects generated lately, there are nonetheless challenges to beat that jeopardize its scientific software in common apply. The predominant aim of this overview is to offer an in-depth understanding of the present standing and implementation of 3D bioprinting expertise in the ophthalmology subject in an effort to manufacture related tissues reminiscent of cornea, retina and conjunctiva.
Goat IgG Isotype Control |
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GWB-B5EB81 | GenWay Biotech | 100 TESTS | Ask for price |
Goat IgG Isotype Control |
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GWB-9C0B03 | GenWay Biotech | 100 TESTS | Ask for price |
Goat IgG Isotype Control |
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GWB-7B95C3 | GenWay Biotech | 0.5 mg | Ask for price |
Goat IgG Isotype Control |
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GWB-E035B6 | GenWay Biotech | 100 TESTS | Ask for price |
Goat IgG Isotype Control |
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GWB-D15A0C | GenWay Biotech | 100 TESTS | Ask for price |
PE Goat IgG Isotype Control |
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E16FGCP006-100 | EnoGene | 100 tests | EUR 368.33 |
Description: Available in various conjugation types. |
Goat F(ab )2 IgG Isotype Control |
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GWB-4FA356 | GenWay Biotech | 100 TESTS | Ask for price |
Goat F(ab')2 IgG Isotype Control |
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abx405076-05mg | Abbexa | 0.5 mg | EUR 493.2 |
Goat F(ab )2 IgG Isotype Control |
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GWB-B1F87E | GenWay Biotech | 100 TESTS | Ask for price |
Goat F(ab )2 IgG Isotype Control |
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GWB-A21E37 | GenWay Biotech | 0.5 mg | Ask for price |
Goat F(ab )2 IgG Isotype Control |
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GWB-ECE6CB | GenWay Biotech | 100 TESTS | Ask for price |
Goat F(ab )2 IgG Isotype Control |
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GWB-827F32 | GenWay Biotech | 100 TESTS | Ask for price |
Goat F(ab )2 IgG Isotype Control |
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GWB-953EBC | GenWay Biotech | 100 TESTS | Ask for price |
Goat F(ab )2 IgG Isotype Control |
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GWB-712793 | GenWay Biotech | 100 TESTS | Ask for price |
Goat F(ab )2 IgG Isotype Control |
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GWB-CF433F | GenWay Biotech | 5 mg | Ask for price |
Goat F(ab')2 IgG Isotype Control |
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abx405076-250g | Abbexa | 250 µg | EUR 300 |
Goat IgG-PE conjugate (isotype control) |
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20011-PE | Alpha Diagnostics | 100 tests | EUR 270 |
Goat IgG-HRP conjugate (isotype control) |
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20011-HP | Alpha Diagnostics | 100 ug | EUR 196.8 |
Goat F(ab')2 IgG Isotype Control (PE) |
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abx405078-100g | Abbexa | 100 µg | EUR 437.5 |
Goat IgG-FITC conjugate (isotype control) |
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20011-F | Alpha Diagnostics | 100 ug | EUR 196.8 |
Goat F(ab')2 IgG Isotype Control (RPE) |
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abx405078-05ml | Abbexa | 0.5 ml | EUR 644.4 |
Goat F(ab')2 IgG Isotype Control (FITC) |
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abx405077-100tests | Abbexa | 100 tests | EUR 594 |
Goat F(ab')2 IgG Isotype Control (FITC) |
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abx405077-100g | Abbexa | 100 µg | EUR 387.5 |
Alexa Fluor® 647 Goat IgG Isotype Control |
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E16FGCK006-100 | EnoGene | 100 tests | EUR 563.33 |
Description: Available in various conjugation types. |
Goat IgG (fc)-HRP conjugate (isotype control) |
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20011-Fc-HP | Alpha Diagnostics | 100 ug | EUR 196.8 |
Normal Goat Polyclonal Isotype Control IgG |
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nAP-0014 | Angio Proteomie | 1mg | EUR 459 |
Goat IgG (fc)-FITC conjugate (isotype control) |
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20011-Fc-F | Alpha Diagnostics | 100 ug | EUR 196.8 |
Goat IgG (-ve control for flow cytometry) (isotype control) |
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20011-100 | Alpha Diagnostics | 100 test | EUR 123.6 |
Goat IgG (fc)-Biotin conjugate (isotype control) |
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20011-Fc-B | Alpha Diagnostics | 100 ug | EUR 196.8 |
Goat IgG, purified (serum non-immune, isotype control) |
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20011-25 | Alpha Diagnostics | 25 mg | EUR 562.8 |
Goat IgG, purified (serum non-immune, isotype control) |
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20011-5 | Alpha Diagnostics | 5 mg | EUR 343.2 |
Rat IgG-PE conjugate (isotype control) (Isotype control) |
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20005-PE | Alpha Diagnostics | 25 tests | EUR 242.4 |
Rat IgG-HRP conjugate (isotype control) (Isotype control) |
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20005-HP | Alpha Diagnostics | 100 ug | EUR 196.8 |
Rat IgG-FITC conjugate (isotype control) (Isotype control) |
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20005-F | Alpha Diagnostics | 100 ug | EUR 196.8 |
Rat IgG Isotype Control |
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31-AR15 | Fitzgerald | 10 mg | EUR 183 |
Description: Purified Rat IgG Isotype Control |
Rat IgG Isotype Control |
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GWB-37FCE4 | GenWay Biotech | 10 mg | Ask for price |
Rat IgG Isotype Control |
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GWB-4BFFB2 | GenWay Biotech | 0.5 mg | Ask for price |
Rat IgG Isotype Control |
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GWB-1E8B74 | GenWay Biotech | 0.1 mg | Ask for price |
Rat IgG Isotype Control |
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GWB-B6F703 | GenWay Biotech | 0.1 mg | Ask for price |
Dog IgG Isotype Control |
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GWB-323C1E | GenWay Biotech | 5 mg | Ask for price |
Rat IgG Isotype Control |
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GWB-7A6404 | GenWay Biotech | 0.1 mg | Ask for price |
Rat IgG Isotype Control |
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GWB-D9CFB7 | GenWay Biotech | 0.1 mg | Ask for price |
Rat IgG Isotype Control |
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GWB-76BDF3 | GenWay Biotech | 0.1 mg | Ask for price |
Rat IgG Isotype Control |
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GWB-787682 | GenWay Biotech | 0.1 mg | Ask for price |
Rat IgG Isotype Control |
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GWB-F39C54 | GenWay Biotech | 0.5 mg | Ask for price |
Rat IgG Isotype Control |
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GWB-F7A192 | GenWay Biotech | 0.5 mg | Ask for price |
Rat IgG Isotype Control |
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GWB-CFDA81 | GenWay Biotech | 0.1 mg | Ask for price |
Rat IgG Isotype Control |
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GWB-BEE47C | GenWay Biotech | 0.1 mg | Ask for price |
OOSA10406-500UG - GOAT F(ab')2 IgG NEGATIVE CONTROL Negative/Isotype Control |
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OOSA10406-500UG | Aviva Systems Biology | 0.5mg | EUR 339 |
Rat IgG-Biotin conjugate (isotype control) (Isotype control) |
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20005-B | Alpha Diagnostics | 100 ug | EUR 196.8 |
Human IgG Isotype Control |
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GWB-2CF422 | GenWay Biotech | 1.0 mg | Ask for price |
Mouse IgG Isotype Control |
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GWB-2F1CBA | GenWay Biotech | 0.1 mg | Ask for price |
Mouse IgG Isotype Control |
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GWB-552B59 | GenWay Biotech | 0.1 mg | Ask for price |
Human IgG Isotype Control |
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GWB-38F945 | GenWay Biotech | 1 ml | Ask for price |
Mouse IgG Isotype Control |
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GWB-4662CD | GenWay Biotech | 0.1 mg | Ask for price |
Mouse IgG Isotype Control |
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GWB-46ECA9 | GenWay Biotech | 0.5 mg | Ask for price |
Mouse IgG Isotype Control |
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GWB-1B0AB3 | GenWay Biotech | 0.5 mg | Ask for price |
Mouse IgG Isotype Control |
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GWB-1BE5E5 | GenWay Biotech | 10 mg | Ask for price |
Sheep IgG Isotype Control |
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GWB-1E6DA3 | GenWay Biotech | 1 mg | Ask for price |
Sheep IgG Isotype Control |
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GWB-9688FE | GenWay Biotech | 0.1 mg | Ask for price |
Mouse IgG Isotype Control |
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GWB-E00547 | GenWay Biotech | 1 ml | Ask for price |
Mouse IgG Isotype Control |
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GWB-EDB4A9 | GenWay Biotech | 0.5 mg | Ask for price |
Mouse IgG Isotype Control |
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GWB-949104 | GenWay Biotech | 0.1 mg | Ask for price |
Sheep IgG Isotype Control |
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GWB-710114 | GenWay Biotech | 5 mg | Ask for price |
Mouse IgG Isotype Control |
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GWB-75892E | GenWay Biotech | 0.1 mg | Ask for price |
Mouse IgG Isotype Control |
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GWB-D166E3 | GenWay Biotech | 0.1 mg | Ask for price |
Human IgG Isotype Control |
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GWB-BDF954 | GenWay Biotech | 1 ml | Ask for price |
Mouse IgG Isotype Control |
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GWB-BEF412 | GenWay Biotech | 0.1 mg | Ask for price |
Mouse IgG Isotype Control |
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IC002-100ul | SAB | 100ul | EUR 146.4 |
Mouse IgG Isotype Control |
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abx127121-100l | Abbexa | 100 µl | EUR 150 |
Mouse IgG Isotype Control |
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abx127121-1ml | Abbexa | 1 ml | Ask for price |
Mouse IgG Isotype Control |
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abx127121-200l | Abbexa | 200 µl | Ask for price |
Human IgG Isotype Control |
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DAGIC1333 | Creative Diagnostics | 10 mg | EUR 724.5 |
Description: Human |
Rabbit IgG Isotype Control |
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GWB-1EF918 | GenWay Biotech | 100 TESTS | Ask for price |
Rabbit IgG Isotype Control |
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GWB-12A897 | GenWay Biotech | 100 TESTS | Ask for price |
Rabbit IgG isotype control |
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AC042 | Abclonal | 100μL | EUR 292.5 |
Description: None |
Rabbit IgG Isotype Control |
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abx125003-100ul | Abbexa | 100 ul | EUR 243.6 |
Rabbit IgG Isotype Control |
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GWB-F3BC41 | GenWay Biotech | 10 mg | Ask for price |
Rabbit IgG Isotype Control |
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IC001-100ul | SAB | 100ul | EUR 146.4 |
Rabbit IgG Isotype Control |
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abx125003-100l | Abbexa | 100 µl | EUR 150 |
Rabbit IgG Isotype Control |
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abx125003-1ml | Abbexa | 1 ml | Ask for price |
Rabbit IgG Isotype Control |
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abx125003-200l | Abbexa | 200 µl | Ask for price |
Rabbit IgG Isotype Control |
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CABT-B8382 | Creative Diagnostics | 500 µg | EUR 598.5 |
Description: Rabbit |
Hamster IgG Isotype Control |
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GWB-528DB9 | GenWay Biotech | 0.1 mg | Ask for price |
Hamster IgG Isotype Control |
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GWB-419E75 | GenWay Biotech | 0.1 mg | Ask for price |
Hamster IgG Isotype Control |
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GWB-47E59E | GenWay Biotech | 0.5 mg | Ask for price |
Hamster IgG Isotype Control |
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GWB-4DBCD9 | GenWay Biotech | 0.1 mg | Ask for price |
Hamster IgG Isotype Control |
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GWB-1A8D7A | GenWay Biotech | 0.1 mg | Ask for price |
Hamster IgG Isotype Control |
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GWB-30C10C | GenWay Biotech | 0.1 mg | Ask for price |
Hamster IgG Isotype Control |
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GWB-3114BE | GenWay Biotech | 0.5 mg | Ask for price |
Hamster IgG Isotype Control |
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GWB-3413D0 | GenWay Biotech | 0.1 mg | Ask for price |
Hamster IgG Isotype Control |
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GWB-6571A8 | GenWay Biotech | 0.5 mg | Ask for price |
Hamster IgG Isotype Control |
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GWB-EE081F | GenWay Biotech | 0.5 mg | Ask for price |
Hamster IgG Isotype Control |
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GWB-C224BD | GenWay Biotech | 0.1 mg | Ask for price |
IgG Isotype Control antibody |
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10R-6524 | Fitzgerald | 50 ug | EUR 123 |
Description: Armenian Hamster monoclonal IgG Isotype Control antibody |
IgG Isotype Control antibody |
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10R-6525 | Fitzgerald | 50 ug | EUR 123 |
Description: Syrian Hamster monoclonal IgG Isotype Control antibody |
IgG Isotype Control antibody (PE) |
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61R-1337 | Fitzgerald | 200 ug | EUR 224 |
Description: Armenian Hamster monoclonal IgG Isotype Control antibody (PE) |
IgG Isotype Control antibody (PE) |
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61R-1338 | Fitzgerald | 50 ug | EUR 224 |
Description: Syrian Hamster monoclonal IgG Isotype Control antibody (PE) |
FITC Rabbit IgG - Isotype control |
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DB-1000 | DB Biotech | 100 tests | EUR 506.4 |
FITC Rabbit IgG - Isotype control |
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DB1000 | DB Biotech | 100 tests | EUR 506.4 |
Rabbit IgG Isotype Control (FITC) |
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abx227001-100g | Abbexa | 100 µg | EUR 225 |
IgG Isotype Control antibody (FITC) |
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61R-1136 | Fitzgerald | 50 ug | EUR 201 |
Description: Armenian Hamster monoclonal IgG Isotype Control antibody (FITC) |
IgG Isotype Control antibody (FITC) |
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61R-1800 | Fitzgerald | 25 ug | EUR 175 |
Description: Rabbit polyclonal IgG Isotype Control antibody (FITC) |
Hamster (Syrian) IgG Isotype Control |
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abx405032-025mg | Abbexa | 0.25 mg | EUR 460.8 |
Syrian Hamster IgG Isotype Control |
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SIGGA-100 | ImmunoStep | 100 µg | EUR 688.99 |
Syrian Hamster IgG Isotype Control |
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SIGGB-200 | ImmunoStep | 200 µg | EUR 566.69 |
Syrian Hamster IgG Isotype Control |
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SIGGF-200 | ImmunoStep | 200 µg | EUR 654.05 |
Syrian Hamster IgG Isotype Control |
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SIGGPE-100 | ImmunoStep | 100 µg | EUR 619.1 |
Syrian Hamster IgG Isotype Control |
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SIGGPP5.5-100 | ImmunoStep | 100 µg | EUR 811.3 |
Syrian Hamster IgG Isotype Control |
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SIGGPP5.5-25 | ImmunoStep | 25 µg | EUR 426.91 |
Syrian Hamster IgG Isotype Control |
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SIGGPU-500 | ImmunoStep | 500 µg | EUR 514.27 |
IgG Isotype Control antibody (biotin) |
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61R-1586 | Fitzgerald | 50 ug | EUR 198 |
Description: Armenian Hamster monoclonal IgG Isotype Control antibody (biotin) |
Special consideration is paid to the description of the mostly employed bioprinting strategies, and the most related eye tissue engineering research carried out by 3D bioprinting expertise at preclinical stage. In addition, different related points associated to make use of of 3D bioprinting for ocular drug supply, in addition to each moral and regulatory points, are analyzed. Through this overview, we intention to lift consciousness amongst the analysis neighborhood and report latest advances and future instructions in an effort to apply this superior remedy in the eye tissue regeneration subject.